馬偕醫學院 Mackay Medical College
Institute of Long-Term Care
Primary Faculty
Tsai, Shin-Yi
Current Position(s)

Associate Professor; Attending physician

Major Degree

Doctor of Public Health, Johns Hopkins University
Master of Anatomy and Cell biology, National Taiwan University

Previous Positions

Attending physician

Specialty

Laboratory medicine; clinical pathology

Teaching Courses

I. MMC: Laboratory Diagnosis; Laboratory Diagnosis Practice; Infectious Diseases; Leadership and Management; Data Mining for Smart Health; Health policy and data mining II. MMH: Training Program for PGY Clinical Teacher and Bedside Teaching

Honors

Honors pass in the Dr PH Comprehensive Examination in Jan, 2014
Best Oral Presentation Award, Symposium of Taiwan Society of Clinical Pathology and Laboratory Medicine, Nov. 20, 2016, Taipei

E-Mail

tsaisy@mmc.edu.tw

Research Interests

Computerized Clinical Decision Support Systems; Clinical Microbiology/ Infectious Diseases; Microfluidic Devices for Biomedical Applications; Transfusion Medicine; Molecular Diagnosis, Genomics and Risk Calculation of Diseases; Data Analysis and Data Mining

Representative Publications
  1. Han-Jen Hsu, Hsun Chang, Cheng-Li Lin, Wei-Cheng Yao, Chung-Lieh Hung, Shin-Pin Pang, Chien-Feng KuoShin-Yi Tsai*.  Increased risk of chronic fatigue syndrome following pneumonia: A population-based Cohort study. Journal of Infection and Public Health. Vol.17:e102495. Aug. 2024. (SCI/SCIE)
  2. Hsun ChangChien-Feng Kuo, Teng-Shun Yu, Liang-Yin Ke, Chung-Lieh HungShin-Yi Tsai*.  Increased risk of chronic fatigue syndrome following infection: a 17-year population-based cohort study. Journal of Translational Medicine. Vol.21-No.1:e804. Nov. 2023. (SCI/SCIE)
  3. Kuo-Tzu Sung, Hung-Yu Chang ,  Nai‐Wei Hsu,  Wen‐Hung Huang,  Yueh‐Hung LinChun-Ho YunChih-Chung Hsiao, Chien-Yi Hsu, Shin-Yi Tsai,  Ying‐Ju Chen, Cheng-Ting TsaiCheng‐Huang SuTa‐Chuan Hung, Charles Jia‐Yin Hou,  Hung‐I YehChung-Lieh Hung.  Penalized Model‐Based Unsupervised Phenomapping Unravels Distinctive HFrEF Phenotypes With Improved Outcomes Discrimination From Sacubitril/Valsartan Treatment Independent of MAGGIC Score. Journal of the American Heart Association. Vol.12-No.18:e028860. Sep. 2023. (SCI/SCIE)
  4. Yu-Han Liao, Kung-Pei Tang, Chih-Yu Chou, Chien-Feng KuoShin-Yi Tsai*.  Assessment of factors influencing physicians’ intention to prescribe transfusion using the theory of planned behavior. BMC HEALTH SERVICES RESEARCH. Vol.23-No.1:e973. Sep. 2023. (SCI/SCIE)
  5. Chi Chen,  Hei-Tung Yip,  Kam-Hang Leong,  Wei-Cheng Yao,  Chung-Lieh Hung,  Ching-Huang Su,  Chien-Feng Kuo ,  Shin-Yi Tsai*.  Presence of depression and anxiety with distinct patterns of pharmacological treatments before the diagnosis of chronic fatigue syndrome: a population-based study in Taiwan. Journal of Translational Medicine. Vol.21-No.1:e98. Feb. 2023. (SCI/SCIE)
  6. Wei-Cheng Yao, Kam-Hang Leong, Lu-Ting Chiu, Po-Yi Chou, Li-Chih Wu, Chih-Yu CHou, Chien-Feng Kuo, Shin-Yi Tsai*.  The trends in the incidence and thrombosis-related comorbidities of antiphospholipid syndrome: a 14-year nationwide population-based study. Thrombosis Journal. Vol.20-No.1:e50. Sep. 2022. (SCI/SCIE)
  7. Kam‑Hang Leong,  Hei‑Tung Yip, Chien‑Feng KuoShin‑Yi Tsai*.  Treatments of chronic fatigue syndrome and its debilitating comorbidities: a 12-year population-based study.. Journal of Translational Medicine. Vol.20-No.1:e268. Jun. 2022. (SCI/SCIE)
  8. Nai-Wei Hsu, Kai-Chen Chou, Yu-Ting Tina Wang, Chung-Lieh HungChein-Feng KuoShin-Yi Tsai*.  Building a model for predicting metabolic syndrome using artificial intelligence based on an investigation of whole-genome sequencing. Journal of Translational Medicine. Vol.20-No.1:e190. Apr. 2022. (SCI/SCIE)
  9. Chanchal Chandramouli, Chi-In Lo, Jui-Peng Tsai, Yau-Huei Lai, Chih-Chung HsiaoShin‐Yi TsaiChun-Ho YunKuo-Tzu SungTa-Chuan HungJen-Yuan KuoJiun-Lu LinCharles Jia-Yin Hou.  Asociation of Female Menopause with Atrioventricular Mechanics and Outcomes. Frontiers in Cardiovascular Medicine. Vol.9:e804336. Apr. 2022. (SCI/SCIE)
  10. Tse‑Yen Yang, Cheng‑Li Lin, Wei‑Cheng Yao,  Chon‑Fu Lio,  Wen-Po Chiang, Kuan Lin, Chien‑Feng KuoShin‑Yi Tsai**.  How mycobacterium tuberculosis infection could lead to the increasing risks of chronic fatigue syndrome and the potential immunological effects: a population-based retrospective cohort study. Journal of Translational Medicine. Vol.20-No.1:e99. Feb. 2022. (SCI/SCIE)
  11. Hsun Chang, Yu-Hung Wu, Chia-Chin Chiang, Yu-Ting Tina Wang,  Kam-Hang Leong, Shin-Yi Tsai*.  Cutaneous infection with Prototheca wickerhamii treated successfully with Voriconazole. International Journal of Gerontology. Vol.16-No.3:305-307. Jan. 2022. (SCI/SCIE)
  12. Chung-Lieh HungKuo-Tzu SungShun-Chuan ChangYen-Yu Liu Jen-Yuan KuoCheng-Huang SuShin-Yi TsaiChia-Yuan LiuAn-Sheng LeeShih-Wei WangCharles Jia-Yin HouTa-Chuan HungHung-I Yeh, Wen-Hung Huang, Chuan-Chuan Liu, Szu-Hua Pan.  Variant Aldehyde Dehydrogenase 2 (ALDH2*2) as a Risk Factor for Mechanical LA Substrate Formation and Atrial Fibrillation with Modest Alcohol Consumption in Ethnic Asians. Biomolecules. Vol.11-No.11:e1559. Oct. 2021. (SCI/SCIE)
  13. Leiyu Shi ,  Cheng-Li Lin, Ching-Huang Su, Keng-Chian Lin, Kam-Hang Leong, Yu-Ting Tina Wang, Chien-Feng Kuo, Shin-Yi Tsai*.  The risk of developing Osteoporosis in Hemolytic Anemia-what aggravates the Bone loss?. Journal of Clinical Medicine. Vol.10-No.15:e3364-e3364. Jul. 2021. (SCI/SCIE)
  14. Wei‑ChengYao, Hsuan‑Ju Chen, Kam‑Hang Leong , Kai‑Lan Chang, Yu‑TingTina Wang, Li‑ChinWu,  Po‑YaTung, Chien‑Feng Kuo, Che‐Chen Lin, Shin‐Yi Tsai*.  The risk of fibromyalgia in patients with iron deficiency anemia: a nationwide population‐based cohort study. Scientific Reports. Vol.11:e10496-e10496. May. 2021. (SCI/SCIE)
  15. Leiyu Shi, Chien-Feng Kuo, Cheng-Li Lin, Wei-Cheng Yao, Hsiang-Ting Chen, Chon-Fu Lio, Yu-Ting Tina Wang, Ching-Huang Su , Nai-Wei Hsu, Shin-Yi Tsai*.  How peptic ulcer disease could potentially lead to the lifelong, debilitating effects of chronic fatigue syndrome: an insight. Scientific Reports. Vol.11:7520-7520. Apr. 2021. (SCI)
  16. Shin-Yi Tsai*, Chon-Fu Lio, Shou-Chuan Shih, Cheng-Jui Lin, Yu-Tien Chen, Chia-Meng Yu, Fang-Ju Sun, Chien-Feng Kuo, Xiaofeng Jia*.  The predisposing factors of AKI for prophylactic strategies in burn care. PeerJ. Vol.8:e9984:1-15. Sep. 2020. (SCI)
  17. Chien-Feng Kuo,  Chon Fu Lio,  Hsiang-Ting Chen,  Yu-Ting Tina Wang, Kevin Sheng-Kai Ma,  Yi Ting Chou,  Fu-Chieh Chang, Shin-Yi Tsai*.  Discordance of vancomycin minimum inhibitory concentration for methicillin-resistant Staphylococcus aureus at 2 μg/mL between Vitek II, E-test, and Broth Microdilution. PeerJ. Vol.8:e8963:1-16. May. 2020. (SCI)
  18. Shin-Yi Tsai*, Chon-Fu Lio, Wei-Cheng Yao, Chang-Pan Liu, Shou-Chuan Shih, Tina Yu-Ting Wang, Kam-Hang Leong, Fang-Ju Sun, Chien-Feng Kuo*.  Cost-drivers of medical expenses in burn care management. Burns. Vol.46-No.4:817-824. Apr. 2020. (SCI)
  19. Shin‑Yi Tsai*, Hsuan‑Ju Chen, Chi Chen, Chon‑Fu Lio, Chien‑Feng Kuo, Kam‑Hang Leong, Yu‑Ting Tina Wang, Tse‑Yen Yang, Ching‑Hui You, Wei‑Sheng Wang*.  Increased risk of chronic fatigue syndrome following psoriasis: a nationwide population-based cohort study. Journal of Translational Medicine. Vol.17-No.154:1-10. May. 2019. (SCI)
  20. Shin‑Yi Tsai*, Hsuan‑Ju Chen, Chon‑Fu Lio, Chien‑Feng Kuo, An‑Chun Kao, Wei‑Shieng Wang, Wei‑Cheng Yao, Chi Chen, Tse‑Yen Yang*.  Increased risk of chronic fatigue syndrome in patients with inflammatory bowel disease: a population‑based retrospective cohort study. Journal of Translational Medicine. Vol.17-No.55:1-8. Feb. 2019. (SCI)
  21. Chon-Fu Lio, Hou-Hon Cheong, Chon-Hou Un, Iek-Long Lo, Shin-Yi Tsai*.  The association between meteorological variables and road traffic injuries: a study from Macao. Peer J. Vol.7-No.e6438:1-13. Feb. 2019. (SCI)
  22. Shin-Yi Tsai*, Yi-Ting Chou, Mon-Huan Tsai.  Investigation of whole-Genome Genotyping and Whole-Genome Sequencing in Metabolic Syndrome, a circadian Rhythm-Related Disease.. Basic & Clinical Pharmacology & Toxicology. Vol.V124(S1):8-8. Dec. 2018. (SCI)
  23. Shin‑Yi Tsai*,  Cheng‑Li Lin,  Shou‑Chuan Shih,  Cheng‑Wei Hsu,  Kam‑Hang Leong, Chien‑Feng Kuo, Chon‑Fu Lio, Yu‑Tien Chen,  Yan‑Jiun Hung, Leiyu Shi*.  Increased risk of chronic fatigue syndrome following burn injuries. Journal of Translational Medicine. Vol.16-No.342:1-13. Dec. 2018. (SCI)
  24. Chih-Sheng Chen, Hui-Man Cheng, Hsuan-Ju Chen, Shin-Yi Tsai, Chia-Hung Kao, Hui-Ju Lin, Lei Wan, Tse-Yen Yang.  Dry eye syndrome and the subsequent risk of chronic fatigue syndrome-a prospective population-based study in Taiwan. Oncotarget. Vol.9-No.55:30684-30703. Jul. 2018. (其它地區具同儕審核機制之期刊)
  25. Gehua Zhen, Huanwen Chen, Shin‐Yi Tsai,  Jian Zhang, Tongyi Chen,  Xiaofeng Jia.  Long-term feasibility and biocompatibility of directly microsurgically implanted intrafascicular electrodes in free roaming rabbits. Journal of Biomedical Materials Research Part B: Applied Biomaterials. Vol.12:1-1. Apr. 2018. (SCI)
  26. Shin-Yi Tsai*, Hsuan-Ju Chen, Chon-Fu Lio, Hui-Ping Ho, Chien-Feng Kuo, Xiaofeng Jia, Chi Chen, Yu-Tien Chen, Yi-Ting Chou, Tse-Yen Yang, Fang-Ju Sun, Leiyu Shi*.  Increased risk of herpes zoster in patients with psoriasis: A population-based retrospective cohort study. PLos One. Vol.12-No.8:e0179-e0179. Aug. 2017. (SCI)
  27. Chien-Feng Kuo, Chon-Fu Lio, Chin Chen, Wei-Han Huang, Hui-Ping Ho, Jyh-Seng Wang, Shin-Yi Tsai*.  Prognostic Factors of Fournier’s Gangrene in the Elderly: Experiences of a Medical Center in Southern Taiwan. International journal of gerontology. Vol.10:151-155. Aug. 2016. (SCI)
  28. Tsai SY, Lin CL, Wong YC, Yang TY, Kuo CF, Cheng JM, Wang JS, Kao CH.  Increased Risk of Herpes Zoster Following Dermatomyositis and Polymyositis: A Nationwide Population-Based Cohort Study.. Medicine (Baltimore). Vol.94-No.28:e1138-e1138. Jul. 2015. (SCI)
  29. Tse-Yen Yang, Haung-Tsung Kuo, Hsuan-Ju Chen, Chih-Sheng Chen, Wei-Ming Lin, Shin-Yi Tsai, Chua-Nan Kuo, Chia-Hung Kao.  Increased Risk of Chronic Fatigue Syndrome Following Atopy: A Population-Based Study. Medicine (Baltimore). Vol.94-No.29:1211-1211. Jul. 2015. (SCI)
  30. Tsai S-YT, Chang MT, Lin KHL, Huang HCH, Chen CPC, Lin ML.  Surviving hemolytic disease of the new born from high titer anti-E (1:254), a case report. Vox Sanguinis. Vol.109:276-276. Jun. 2015. (SCI)
  31. Tsai SY, Yang TY, Lin CL, Tsai YH, Kuo CF, Kao CH.  Increased Risk of Varicella Zoster Virus Infection in Inflammatory Bowel Disease in an Asian Population: A Nationwide Population-Based Cohort Study. International Journal of Clinical Practice. Vol.69-No.2:228-234. Feb. 2015. (SCI)
  32. Tsai SY*, Yang TY, Chen HJ, Chen CS, Lin WM, Shen WC, Kuo CN, Kao CH.  Increased Risk of Chronic Fatigue Syndrome Following Herpes Zoster: A Population-Based Study. European Journal of Clinical Microbiology & Infectious Diseases. Vol.33-No.9:1653-1659. Sep. 2014. (SCI)
  33. Chan YS, Tsai SY, Chang HL, Hsiao LC, Ho HT, Lin J, Lin M.  An Intravascular Hemolytic Transfusion Reaction due to Anti-Mia in Taiwan: a Case report and a Review of the lecture. Vox Sanguinis. Vol.107:176-176. May. 2014. (SCI)
  34. Tsai SY, Chang HL, Chang FC, Wang CL, Chang YS, Yu LC, Lin M.  The Analysis of Two Cases of Jk Null Phenotype with Anti-Jk3 in a Medical Center in Northern Taiwan. Vox Sanguinis. Vol.107:170-170. May. 2014. (SCI)
  35. Tsai SY, Er TK, Lin CW, Chang JG.  Comprehensive Analysis of UGT1A1 Polymorphisms through High-Resolution Melting Analysis and DNA Sequencing. Clinical Laboratory. Vol.60-No.6:1015-1026. May. 2014. (SCI)
  36. Jin Li, Gehua Zhen, Shin-Yi Tsai , Xiaofeng Jia.  Epidermal Stem Cells in Orthopaedic Regenerative Medicine. International Journal of Molecular Sciences. Vol.14:11626-11642. May. 2013. (SCI)
  37. Chien-Feng Kuo, Shin-Yi Tsai*, Te-Chu Liu, Cheng-Chih Lin, Chang-Pan Liu, Chun-Ming Lee.  Clinical characteristics and treatment outcomes of patients with tubo-ovarian abscess at a tertiary care hospital in Northern Taiwan.. Journal of Microbiology, Immunology and Infection. Vol.45-No.1:58-64. Dec. 2011. (SCI)
  38. Xiaofeng Jia, Shinyi Tsai, Gehua Zhen,  Adrian Velasquez, Matthew A Koenig, Carlos A Pardo, Nitish V Thakor, Romergryko G Geocadin.  Microglial Activity and Therapeutic Hypothermia Post Cardiac Arrest Resuscitation in Rats.. Circulation. Vol.118:1450-1451. Oct. 2008. (SCI)
  39. Jia X, Tsai S, Zhen G, Velasquez A, Koenig MA, Pardo CA,  Thakor NV, Geocadin RG .  Brain Cellular Response and Therapeutic Hypothermia Post Cardiac Arrest Resuscitation in Rats. Neurocritical Care. Vol.9-No.1:S156-S156. May. 2008. (SCI)
  40. Xiaofeng Jia, Anand Venkatramana, Shinyi Tsai, Gehua Zhen,  Yujie Wang, Matthew A. Koenig, Nitish V. Thakor, Romergryko G.  Temperature Manipulation Alters Early EEG Bursting after Cardiac Arrest in Rats. Neurocritical Care. Vol.1:PP101-PP101. Jul. 2007. (SCI)

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